The research teams of the institute dedicate their research to understanding cell signaling pathways and manipulating them for the development of novel therapeutic strategies. They are mainly focusing on two scientific questions:
- Study the pathways that protect genome integrity by epigenetic, transcriptional or DNA repair mechanisms, and how the deregulation of these pathways contribute to cancer.
- Study the signaling pathways at the cell membrane and their importance for pain, inflammation and pathogenicity.
Find out more about our research teams:
- Poly (ADP-ribosyl)ation and genome integrity (Team F. Dantzer)
- Nuclear signaling and cancer (Team K. Zanier)
- Replisome dynamics and cancer (Team B. Chatton)
- Chemobiological intervention (Team G. Zuber/E. Weiss)
- Epigenetic regulation of cell identity (Team M. Weber)
- GPCRs, pain and inflammation (Team F. Simonin)
- Metals and microorganisms: biology, chemistry and applications (Team I. Schalk/G. Mislin)
- Neuroimmunology and peptide therapy (Team H. Jeltsch-David/S. Muller)
- GPCRs and cardiobiology (Team C. Nebigil)