Publications

Srinivasa Reddy Bonam , Sylviane Muller , Jagadeesh Bayry & Daniel J. Klionsky (2020). Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine. Autophagy, doi.org/10.1080/15548627.2020.1779467

Narasaraju T, Tang BM, Herrmann M, Muller S, Chow VTK, Radic M (2020). Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19. Frontiers in Pharmacology 11:870.

Voynova E, Lefebvre F, Qadri A, Muller S (2020). Correction of autophagy impairment inhibits pathology in the NOD.H-2h4 mouse model of primary Sjögren's syndrome. J of Autoimmunity, 108:102418.

Bonam SR, Tschan MP, Bayry J, Muller S (2020). Progress and challenges in the use of MAP1LC3 as a legitimate marker for measuring dynamic autophagy in vivo. Cells 9:1321.

Bonam SR, Areti A, Komirishetty P, Muller S (2020). Dendrimers in immunotherapy and hormone therapy in Pharmaceutical applications of dendrimers; chapter 10, pp 233-249. Abhay Chauhan and Hitesh Kulhari (Eds) Elsevier.

Bonam SR, Ruff M, Muller S (2019). HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates. Cells 8:849.

Retnakumar SV, Muller S (2019). Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases. Trends Mol Med. 25:516-537.

Bonam SR, Bhunia D, Muller S, Nerella SG, Alvala M, Halmuthur Mahabalarao SK (2019). Novel trisaccharide based phospholipids as immunomodulators. Int Immunopharmacol 74:105684.

Bonam SR, Wang F, Muller S (2019). Lysosomes as a therapeutic target. Nat Rev Drug Discovery 18:923-948.

Arbogast F, Arnold J, Hammann P, Kuhn L, Chicher J, Murera D, Weishaar J, Muller S, Fauny JD, Gros F (2019). ATG5 is required for B cell polarization and presentation of particulate antigens. Autophagy 15:280-294.

Bendorius M, Po C, Muller S, Jeltsch-David H (2018). From systemic inflammation to neuroinflammation: the case of neurolupus. Int J Mol Sci 19:3588.

Bonam SR, Wang F, Muller S (2018). Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option. Journal of Autoimmunity 94:16-32.

Bendorius M, Neeli I, Wang F, Bonam SR, Dombi E, Buron N, Borgne-Sanchez A, Poulton J, Radic M, Muller S (2018). The mitochondrion-lysosome axis in adaptive and innate immunity: Effect of lupus regulator peptide P140 on mitochondria autophagy and NETosis. Front Immunol 9:2158.

Bonam SR, Wu YS, Tunki L, Chellian R, Kumar Halmuthur MS, Muller S, and Pandy V (2018). What Has Come out from Phytomedicines and Herbal Edibles for the Treatment of Cancer? ChemMedChem 13:1854-1872.

Brun S, Schall N, Bonam SR, Bigauta K, Mensah-Nyagana AG, de Sèze J, Muller S (2018). An autophagy-targeting peptide to treat chronic inflammatory demyelinating polyneuropathies. Journal of Autoimmunity 92:114-125.

Li B, Wang F, Schall N, Muller S (2018). Rescue of autophagy and lysosome defects in salivary glands of MRL/lpr mice by a therapeutic phosphopeptide. Journal of Autoimmunity 90: 132-145.

Murera D, Arbogast F, Arnold J, Bouis D, Muller S, Gros F (2018). CD4 T cell autophagy is integral to memory maintenance. Sci Rep 8:5951.

Muller S (2018). Excipients: not so inert? When the excipient plays the role of an active substance, as exemplified in systemic lupus. Swiss Medical Weekly 148:w14631.

Wilhelm M, Wang F, Schall N, Kleinmann JF, Faludi M, Nashi EP, Sibilia J, Martin T, Schaeffer E, Muller S (2018). Lupus Regulator Peptide P140 Represses B Cell Differentiation by Reducing HLA Class II Molecule Overexpression. Arthritis Rheumatol 70:1077-1088.

Kökten T, Gibot S, Lepage P, D’Alessio S, Hablot J, Ndiaye NC, Busby-Venner H, Monot C, Garnier B, Moulin D, Jouzeau JY, Hansmannel H, Danese S, Guéant JL, Muller S, Peyrin-Biroulet L (2018). TREM-1 inhibition restores impaired autophagy activity and reduces colitis in mice. J Crohns Colitis 12:230-244.

Bermúdez M, Arévalo-Pinzón G, Rubio L, Chaloin O, Muller S, Curtidor H, Patarroyo MA (2018). Receptor-ligand and parasite protein-protein interactions in Plasmodium vivax: analysing rhoptry neck proteins 2 and 4. Cell Microbiol 20:e12835.

Wang F, Bonam SR, Schall N, Kuhn L, Hammann P, Chaloin O, Madinier JB, Briand JP, Page N, Muller S (2018). Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival. Sci Rep 8:16820.

Selected publications 2013-2017:

Wang F, Li B, Schall N, Wilhelm M, Muller S (2017). Assessing autophagy in mouse models and patients with systemic autoimmune diseases. Cells 6:16.

Muller S (2017). Autophagie, autoimmunité et maladies autoimmunes. Med Sci 33:319-327.

Brun S, Schall N, Jeltsch-David H, de Sèze J, Muller S (2017). Assessing autophagy in sciatic nerves of a rat model that develops inflammatory autoimmune peripheral neuropathies. Cells 6:30.

Bonam SR, Partidos CD, Halmuthur SKM, Muller S (2017). An overview of novel adjuvants designed for improving vaccine efficacy. Trends Pharmacol Sci 9:771-793.

Muller S, Brun S, René F, de Sèze J, Loeffler JP, Jeltsch-David H (2017). Autophagy in neuroinflammatory diseases. Autoimmunity Rev 16:856-874.

Maueröder C, Schall N, Meyer F, Mahajan A, Garnier B, Hahn J, Kienhöfer D, Hoffmann MH, Muller S (2017). Capability of neutrophils to form NETs is not directly influenced by a CMA-targeting peptide. Front Immunol 8:16.

Jeltsch-David H, Muller S (2016). Autoimmunity, neuroinflammation, pathogen load: a decisive crosstalk in neuropsychiatric SLE. J Autoimmunity 74:13-26.

Muller S, Radic M (2016). Oxidation and mitochondrial origin of NET DNA in lupus. Nature Med 22:126-127.

Arnold J, Murera D, Arbogast F, Fauny JD, Muller S, Gros F (2016). Autophagy is dispensable for B cell development but essential for humoral autoimmune responses. Cell Death Diff 23:853-864.

Wang F, Muller S (2015). Manipulating autophagic processes in autoimmune diseases: a special focus on modulating chaperone-mediated autophagy, an emerging therapeutic target. Front Immunol 6:252.

Macri C, Wang F, Tasset I, Schall N, Page N, Briand JP, Cuervo AM, Muller S (2015). Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide. Autophagy 11:472-486.

Jacquemin J, Schmitt N, Contin-Bordes C, Liu Y, Narayanan P, Seneschal J, Maurouard T, Dougall D, Spence Davizon E, Dumortier H, Douchet I, Raffray L, Richez C, Lazaro E, Duffau P, Truchetet ME, Khoryati L, Mercie P, Couzi L, Merville P, Schaeverbeke T, Viallard JF, Pellegrin JL, Moreau JF, Muller S, Coffman RL, Pascual V, Ueno H, Blanco P (2015). OX40L promotes T follicular helper cell responses in human systemic lupus erythematosus. Immunity 42:1159-1170.

Jeltsch-David H, Muller S (2014). Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. Autoimmunity Rev 13:963-973.

Jeltsch-David H, Muller S (2014). Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers. Nature Rev Neurol 10:579–596.

Gros F, Muller S (2014). Pharmacological regulators of autophagy and their link with modulators of lupus disease. Brit J Pharmacol 171:4337-4359.

Lamanna G, Grillaud M, Macri C, Chaloin O, Muller S, Bianco A (2014). Adamantane-based dendrons for trimerization of the therapeutic P140 peptide. Biomaterials 35:7553-756.

Stricher F, Macri C, Ruff M, Muller S (2013). HSPA8/HSC70 chaperone protein: structure, function and chemical targeting. Autophagy 9:1937–1954.

Zimmer R, Scherbarth HR, Rillo OL, Gomez-Reino J, Muller S (2013). Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial. Ann Rheum Dis 72:1830-1835.