Publications

Moeglin E, Desplancq D, Stoessel A, Massute C, Ranniger J, McEwen AG, Zeder-Lutz G, Oulad-Abdelghani M, Chiper M, Lafaye P, Di Ventura B, Didier P, Poterszman A, Weiss E (2021). A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress. Cancers 13(13):3317. doi: 10.3390/cancers13133317.

Mousson A, Legrand M, Steffan T, Vauchelles R, Carl P, Gies JP, Lehmann M, Zuber G, De Mey J, Dujardin D, Sick E, Rondé P. (2021). Inhibiting FAK–Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells. Cancers 13(8):1871. doi: 10.3390/cancers13081871.

Stoessel A, Groysbeck N, Guyot L, Barret L, Nominé Y, Nguekeu-Zebaze L, Bender A, Voilquin L, Lutz T, Pallaoro N, Blocat M, Deville C, Masson M, Zuber G, Chatton B, Donzeau M (2020). Modular Conjugation of a Potent Anti-HER2 Immunotoxin Using Coassociating Peptides. Bioconjug Chem 31(10):2421-2430. doi: 10.1021/acs.bioconjchem.0c00482.

Conic S, Desplancq D, Ferrand A, Molina N, Weiss E, Tora L (2019). Visualization of Endogenous Transcription Factors in Single Cells Using an Antibody Electroporation-Based Imaging Approach. Methods Mol Biol 2038:209-221.

Ohayon D, De Chiara A, Dang PM, Thieblemont N, Chatfield S, Marzaioli V, Burgener SS, Mocek J, Candalh C, Pintard C, Tacnet-Delorme P, Renault G, Lagoutte I, Favier M, Walker F, Hurtado-Nedelec M, Desplancq D, Weiss E, Benarafa C, Housset D, Marie JC, Frachet P, El-Benna J, Witko-Sarsat V (2019). Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J Exp Med 216(11):2669-2687.

Vigneron M, Dietsch F, Bianchetti L, Dejaegere A, Nominé Y, Cordonnier A, Zuber G, Chatton B, Donzeau M (2019). Self-Associating Peptides for Modular Bifunctional Conjugation of Tetramer Macromolecules in Living Cells. Bioconjug Chem 30:1734-1744. doi: 10.1021/acs.bioconjchem.9b00276

Zuber G, Weiss E, Chiper M (2019). Biocompatible gold nanoclusters: synthetic strategies and biomedical prospects. Nanotechnology 30:352001.

Moeglin E, Desplancq D, Conic S, Oulad-Abdelghani M, Stoessel A, Chiper M, Vigneron M, Didier P, Tora L, Weiss E (2019). Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress. Cancers 11(3):355.

Groysbeck N, Stoessel A, Donzeau M, da Silva EC, Lehmann M, Strub JM, Cianferani S, Dembélé K, Zuber G (2019). Synthesis and biological evaluation of 2.4 nm thiolate-protected gold nanoparticles conjugated to Cetuximab for targeting glioblastoma cancer cells via the EGFR. Nanotechnology 30:184005. doi: 10.1088/1361-6528/aaff0a.

Chiper M, Niederreither K, Zuber G (2018). Transduction Methods for Cytosolic Delivery of Proteins and Bioconjugates Into Living Cells. Adv Healthcare Mater 7(6):e1701040.

Desplancq D, Groysbeck N, Chiper M, Weiss E, Frisch B, Strub J-M, Cianferani S, Zafeiratos S, Moeglin E, Holy X, Favier A L, De Carlo S, Schultz P, Spehner D, Zuber G (2018). Cytosolic Diffusion and Peptide-Assisted Nuclear Shuttling of Peptide-Substituted Circa 102 Gold Atom Nanoclusters in Living Cells. ACS Applied Nano Materials 1:4236–4246.

Conic S, Desplancq D, Ferrand A, Fischer V, Heyer V, Reina San Martin B, Pontabry J, Oulad-Abdelghani M, Babu N K, Wright GD, Molina N, Weiss E, Tora L (2018). Imaging of native transcription factors and histone phosphorylation at high resolution in live cells. J Cell Biol 217:1537-1552.

Conic S, Desplancq D, Tora L, Weiss E (2018). Electroporation of Labeled Antibodies to Visualize Endogenous Proteins and Posttranslational Modifications in Living Metazoan Cell Types. Bio Protoc 8(21). doi: 10.21769/BioProtoc.3069.

Wagner HJ, Wehrle S, Weiss E, Cavallari M, Weber W. (2018). A Two-Step Approach for the Design and Generation of Nanobodies. Int J Mol Sci 19(11):3444.

Dietsch F, Donzeau M, Cordonnier AM, Weiss E, Chatton B, Vigneron M (2017). A fast method for analyzing essential protein mutants in human cells. Biotechniques 62:80-82.

Chiper M, Tounsi N, Kole R, Kichler A, Zuber G (2017). Self-aggregating 1.8kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides. J Control Release 246:60-70.

Akasov R, Zaytseva-Zotova D, Burov S, Leko M, Dontenwill M, Chiper M, Vandamme T, Markvicheva E (2016). Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int J Pharm 506:148-157.

Attia MF, Anton N, Akasov R, Chiper M, Markvicheva E, Vandamme TF (2016). Biodistribution and Toxicity of X-Ray Iodinated Contrast Agent in Nano-emulsions in Function of Their Size. Pharm Res 33:603-614.

Simon-Yarza MT, Baati T, Paci A, Lesueur LL, Seck A, Chiper M, Gref R, Serre C, Couvreur P, Horcajada P (2016). Antineoplastic Busulfan encapsulated in Metal Organic Framework nanocarrier: first in vivo results. J Mater Chem B Mater Biol Med 4:585-588.

Desplancq D, Freund G, Conic S, Sibler AP, Didier P, Stoessel A, Oulad-Abdelghani M, Vigneron M, Wagner J, Mely Y, Chatton B, Tora L, Weiss E (2016). Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells. Exp Cell Res 342:145-158.

Zuber G (2016). Organizing proteins within a delivery system improves cytosolic transfer. Med Sci 32:345-347.

Guilini C, Baehr C, Schaeffer E, Gizzi P, Rufi F, Haiech J, Weiss E, Bonnet D, Galzi JL (2015). New fluorescein precursors for live bacteria detection. Anal Chem 87:8858-8866.

Orlov I, Schertel A, Zuber G, Klaholz B, Drillien R, Weiss E, Schultz P, Spehner D (2015). Live cell immunogold labelling of RNA polymerase II. Sci Rep 5:8324.

Postupalenko V, Desplancq D, Orlov I, Arntz Y, Spehner D, Mely Y, Klaholz BP, Schultz P, Weiss E, Zuber G (2015). Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer. Angew Chem Int Ed Engl 54:10583-10586.

Schaeffer E, Vigneron M, Sibler AP, Oulad-Abdelghani M, Chatton B, Donzeau M (2015). ATF7 is stabilized during mitosis in a CDK1-dependent manner and contributes to cyclin D1 expression. Cell Cycle 14:2655-2666.

Attia MF, Anton N, Chiper M, Akasov R, Anton H, Messaddeq N, Fournel S, Klymchenko AS, Mely Y, Vandamme TF (2014). Biodistribution of X-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core. ACS Nano 8:10537-10550.

Ericson M, Rice K, Zuber G (2014). 13: Macromolecular Conjugates for Non-Viral Nucleic Acid Delivery. Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology. D. Scherman, Imperial College Press: 207-219.

Freund G, Desplancq D, Stoessel A, Weinsanto R, Sibler AP, Robin G, Martineau P, Didier P, Wagner J, Weiss E (2014). Generation of an intrabody-based reagent suitable for imaging endogenous proliferating cell nuclear antigen in living cancer cells. J Mol Recognit 27:549-558.

Li X, Anton N, Zuber G, Vandamme T (2014). Contrast agents for preclinical targeted X-ray imaging. Adv Drug Deliv Rev 76:116-133.

Pinel S, Aman E, Erblang F, Dietrich J, Frisch B, Sirman J, Kichler A, Sibler AP, Dontenwill M, Schaffner F, Zuber G (2014). Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines. J Control Release 182:1-12.

Postupalenko V, Sibler AP, Desplancq D, Nomine Y, Spehner D, Schultz P, Weiss E, Zuber G (2014). Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine. J Control Release 178:86-94.

Chandrashekhar C, Pons B, Muller CD, Tounsi N, Mulherkar R, Zuber G (2013). Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity. Acta Biomaterialia 9:4985-4993.

Chiper M, Herve Aubert K, Auge A, Fouquenet JF, Souce M, Chourpa I (2013). Colloidal stability and thermo-responsive properties of iron oxide nanoparticles coated with polymers: advantages of Pluronic(R) F68-PEG mixture. Nanotechnology 24:395605.

Freund G, Sibler AP, Desplancq D, Oulad-Abdelghani M, Vigneron M, Gannon J, Van Regenmortel MH, Weiss E (2013). Targeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells. MAbs 5:518-522.

Li X, Anton N, Zuber G, Zhao MJ, Messaddeq N, Hallouard F, Fessi H, Vandamme TF (2013). Iodinated alpha-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging. Biomaterials 34:481-491.

Philippe L, Alsaleh G, Pichot A, Ostermann E, Zuber G, Frisch B, Sibilia J, Pfeffer S, Bahram S, Wachsmann D, Georgel P (2013). MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Annals of the Rheumatic Diseases 72:1071-1079.

Pierrat P, Kereselidze D, Wehrung P, Zuber G, Pons F, Lebeau L (2013). Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA. Pharmaceutical Research 30:1362-1379.

Pierrat P, Laverny G, Creusat G, Wehrung P, Strub JM, VanDorsselaer A, Pons F, Zuber G, Lebeau L (2013). Phospholipid-Detergent Conjugates as Novel Tools for siRNA Delivery. Chemistry 19:2344-2355.

Rinaldi AS, Freund G, Desplancq D, Sibler AP, Baltzinger M, Rochel N, Mely Y, Didier P, Weiss E (2013). The use of fluorescent intrabodies to detect endogenous gankyrin in living cancer cells. Exp Cell Res 319:838-849.

Creusat G, Thomann JS, Maglott A, Pons B, Dontenwill M, Guerin E, Frisch B, Zuber G (2012). Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo. J Control Release 157:418-426.

Kaaki K, Herve-Aubert K, Chiper M, Shkilnyy A, Souce M, Benoit R, Paillard A, Dubois P, Saboungi ML, Chourpa I (2012). Magnetic nanocarriers of doxorubicin coated with poly(ethylene glycol) and folic acid: relation between coating structure, surface properties, colloidal stability, and cancer cell targeting. Langmuir 28:1496-1505.

Pierrat P, Creusat G, Laverny G, Pons F, Zuber G, Lebeau L (2012). A Cationic Phospholipid-Detergent Conjugate as a New Efficient Carrier for siRNA Delivery. Chemistry 18:3835-3839.

Schante CE, Zuber G, Herlin C, Vandamme TF (2012). Improvement of hyaluronic acid enzymatic stability by the grafting of amino-acids. Carbohydrate Polymers 87:2211-2216.

Desplancq D, Rinaldi AS, Stoessel A, Sibler AP, Busso D, Oulad-Abdelghani M, Van Regenmortel MH, Weiss E (2011). Single-chain Fv fragment antibodies selected from an intrabody library as effective mono- or bivalent reagents for in vitro protein detection. J Immunol Methods 369:42-50.

Foillard S, Zuber G, Doris E (2011). Polyethylenimine-carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level. Nanoscale 3:1461-1464.

Hallouard F, Anton N, Zuber G, Choquet P, Li X, Arntz Y, Aubertin G, Constantinesco A, Vandamme TF (2011). Radiopaque iodinated nano-emulsions for preclinical X-ray imaging. Rsc Advances 1:792-801.

Schante C, Zuber G, Herlin C, Vandamme TF (2011). Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion. Carbohydrate Polymers 86:747-752.

Schante CE, Zuber G, Herlin C, Vandamme TF (2011). Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications. Carbohydrate Polymers 85:469-489.

Zuber G, Frisch B, Creusat G, Thomann JS (2011). "Polymers for delivering molecules of interest." Patent US 2013/0096177A1.