Publications

Chiper M, Niederreither K, Zuber G (2018). Transduction Methods for Cytosolic Delivery of Proteins and Bioconjugates Into Living Cells. Adv Healthcare Mater 7(6):e1701040.

Desplancq D, Groysbeck N, Chiper M, Weiss E, Frisch B, Strub J-M, Cianferani S, Zafeiratos S, Moeglin E, Holy X, Favier A L, De Carlo S, Schultz P, Spehner D, Zuber G (2018). Cytosolic Diffusion and Peptide-Assisted Nuclear Shuttling of Peptide-Substituted Circa 102 Gold Atom Nanoclusters in Living Cells. ACS Applied Nano Materials 1(8):4236–4246.

Conic S, Desplancq D, Ferrand A, Fischer V, Heyer V, Reina San Martin B, Pontabry J, Oulad-Abdelghani M, Babu N K, Wright GD, Molina N, Weiss E, Tora L (2018). Imaging of native transcription factors and histone phosphorylation at high resolution in live cells. J Cell Biol 217:1537-1552.

Dietsch F, Donzeau M, Cordonnier AM, Weiss E, Chatton B, Vigneron M (2017). A fast method for analyzing essential protein mutants in human cells. Biotechniques 62:80-82.

Chiper M, Tounsi N, Kole R, Kichler A, Zuber G (2017). Self-aggregating 1.8kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides. J Control Release 246:60-70.

Akasov R, Zaytseva-Zotova D, Burov S, Leko M, Dontenwill M, Chiper M, Vandamme T, Markvicheva E (2016). Formation of multicellular tumor spheroids induced by cyclic RGD-peptides and use for anticancer drug testing in vitro. Int J Pharm 506:148-157.

Attia MF, Anton N, Akasov R, Chiper M, Markvicheva E, Vandamme TF (2016). Biodistribution and Toxicity of X-Ray Iodinated Contrast Agent in Nano-emulsions in Function of Their Size. Pharm Res 33:603-614.

Simon-Yarza MT, Baati T, Paci A, Lesueur LL, Seck A, Chiper M, Gref R, Serre C, Couvreur P, Horcajada P (2016). Antineoplastic Busulfan encapsulated in Metal Organic Framework nanocarrier: first in vivo results. J Mater Chem B Mater Biol Med 4:585-588.

Desplancq D, Freund G, Conic S, Sibler AP, Didier P, Stoessel A, Oulad-Abdelghani M, Vigneron M, Wagner J, Mely Y, Chatton B, Tora L, Weiss E (2016). Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells. Exp Cell Res 342:145-158.

Zuber G (2016). Organizing proteins within a delivery system improves cytosolic transfer. Med Sci 32:345-347.

Guilini C, Baehr C, Schaeffer E, Gizzi P, Rufi F, Haiech J, Weiss E, Bonnet D, Galzi JL (2015). New fluorescein precursors for live bacteria detection. Anal Chem 87:8858-8866.

Orlov I, Schertel A, Zuber G, Klaholz B, Drillien R, Weiss E, Schultz P, Spehner D (2015). Live cell immunogold labelling of RNA polymerase II. Sci Rep 5:8324.

Postupalenko V, Desplancq D, Orlov I, Arntz Y, Spehner D, Mely Y, Klaholz BP, Schultz P, Weiss E, Zuber G (2015). Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer. Angew Chem Int Ed Engl 54:10583-10586.

Schaeffer E, Vigneron M, Sibler AP, Oulad-Abdelghani M, Chatton B, Donzeau M (2015). ATF7 is stabilized during mitosis in a CDK1-dependent manner and contributes to cyclin D1 expression. Cell Cycle 14:2655-2666.

Attia MF, Anton N, Chiper M, Akasov R, Anton H, Messaddeq N, Fournel S, Klymchenko AS, Mely Y, Vandamme TF (2014). Biodistribution of X-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core. ACS Nano 8:10537-10550.

Ericson M, Rice K, Zuber G (2014). 13: Macromolecular Conjugates for Non-Viral Nucleic Acid Delivery. Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology. D. Scherman, Imperial College Press: 207-219.

Freund G, Desplancq D, Stoessel A, Weinsanto R, Sibler AP, Robin G, Martineau P, Didier P, Wagner J, Weiss E (2014). Generation of an intrabody-based reagent suitable for imaging endogenous proliferating cell nuclear antigen in living cancer cells. J Mol Recognit 27:549-558.

Li X, Anton N, Zuber G, Vandamme T (2014). Contrast agents for preclinical targeted X-ray imaging. Adv Drug Deliv Rev 76:116-133.

Pinel S, Aman E, Erblang F, Dietrich J, Frisch B, Sirman J, Kichler A, Sibler AP, Dontenwill M, Schaffner F, Zuber G (2014). Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines. J Control Release 182:1-12.

Postupalenko V, Sibler AP, Desplancq D, Nomine Y, Spehner D, Schultz P, Weiss E, Zuber G (2014). Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine. J Control Release 178:86-94.

Chandrashekhar C, Pons B, Muller CD, Tounsi N, Mulherkar R, Zuber G (2013). Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity. Acta Biomaterialia 9:4985-4993.

Chiper M, Herve Aubert K, Auge A, Fouquenet JF, Souce M, Chourpa I (2013). Colloidal stability and thermo-responsive properties of iron oxide nanoparticles coated with polymers: advantages of Pluronic(R) F68-PEG mixture. Nanotechnology 24:395605.

Freund G, Sibler AP, Desplancq D, Oulad-Abdelghani M, Vigneron M, Gannon J, Van Regenmortel MH, Weiss E (2013). Targeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells. MAbs 5:518-522.

Li X, Anton N, Zuber G, Zhao MJ, Messaddeq N, Hallouard F, Fessi H, Vandamme TF (2013). Iodinated alpha-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging. Biomaterials 34:481-491.

Philippe L, Alsaleh G, Pichot A, Ostermann E, Zuber G, Frisch B, Sibilia J, Pfeffer S, Bahram S, Wachsmann D, Georgel P (2013). MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Annals of the Rheumatic Diseases 72:1071-1079.

Pierrat P, Kereselidze D, Wehrung P, Zuber G, Pons F, Lebeau L (2013). Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA. Pharmaceutical Research 30:1362-1379.

Pierrat P, Laverny G, Creusat G, Wehrung P, Strub JM, VanDorsselaer A, Pons F, Zuber G, Lebeau L (2013). Phospholipid-Detergent Conjugates as Novel Tools for siRNA Delivery. Chemistry 19:2344-2355.

Rinaldi AS, Freund G, Desplancq D, Sibler AP, Baltzinger M, Rochel N, Mely Y, Didier P, Weiss E (2013). The use of fluorescent intrabodies to detect endogenous gankyrin in living cancer cells. Exp Cell Res 319:838-849.

Creusat G, Thomann JS, Maglott A, Pons B, Dontenwill M, Guerin E, Frisch B, Zuber G (2012). Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo. J Control Release 157:418-426.

Kaaki K, Herve-Aubert K, Chiper M, Shkilnyy A, Souce M, Benoit R, Paillard A, Dubois P, Saboungi ML, Chourpa I (2012). Magnetic nanocarriers of doxorubicin coated with poly(ethylene glycol) and folic acid: relation between coating structure, surface properties, colloidal stability, and cancer cell targeting. Langmuir 28:1496-1505.

Pierrat P, Creusat G, Laverny G, Pons F, Zuber G, Lebeau L (2012). A Cationic Phospholipid-Detergent Conjugate as a New Efficient Carrier for siRNA Delivery. Chemistry 18:3835-3839.

Schante CE, Zuber G, Herlin C, Vandamme TF (2012). Improvement of hyaluronic acid enzymatic stability by the grafting of amino-acids. Carbohydrate Polymers 87:2211-2216.

Desplancq D, Rinaldi AS, Stoessel A, Sibler AP, Busso D, Oulad-Abdelghani M, Van Regenmortel MH, Weiss E (2011). Single-chain Fv fragment antibodies selected from an intrabody library as effective mono- or bivalent reagents for in vitro protein detection. J Immunol Methods 369:42-50.

Foillard S, Zuber G, Doris E (2011). Polyethylenimine-carbon nanotube nanohybrids for siRNA-mediated gene silencing at cellular level. Nanoscale 3:1461-1464.

Hallouard F, Anton N, Zuber G, Choquet P, Li X, Arntz Y, Aubertin G, Constantinesco A, Vandamme TF (2011). Radiopaque iodinated nano-emulsions for preclinical X-ray imaging. Rsc Advances 1:792-801.

Schante C, Zuber G, Herlin C, Vandamme TF (2011). Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion. Carbohydrate Polymers 86:747-752.

Schante CE, Zuber G, Herlin C, Vandamme TF (2011). Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications. Carbohydrate Polymers 85:469-489.

Zuber G, Frisch B, Creusat G, Thomann JS (2011). "Polymers for delivering molecules of interest." Patent US 2013/0096177A1.