Srinivasa Reddy Bonam, Marc Ru ff and Sylviane Muller (2019). HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates. Cells 2019, 8, 849

Retnakumar SV, Muller S. (2019). Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases. Trends Mol Med. 6:516-537.

Bonam SR, Bhunia D, Muller S, Nerella SG, Alvala M, Halmuthur Mahabalarao SK (2019). Novel trisaccharide based phospholipids as immunomodulators. Int Immunopharmacol. 74:105684.

Bendorius M, Po C, Muller S, Jeltsch-David H (2018). From systemic inflammation to neuroinflammation: the case of neurolupus. Int. J. Mol. Sci. 19, 3588.

Bonam S. R., Wang F. &  Muller S. (2018). Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option. Journal of Autoimmunity 91,16-32.

Bendorius, M., Neeli, I., Wang, F., Bonam, S.R, Dombi, E., Buron, N., Borgne-Sanchez, A., Poulton, J., Radic, M. & Muller, S. (2018). The mitochondrion-lysosome axis in adaptive and innate immunity: Effect of lupus regulator peptide P140 on mitochondria autophagy and NETosis. Front. Immunol. 9:2158.

Bonam SR, Wu YS, Tunki L, Chellian R, Kumar Halmuthur MS, Muller S, and Pandy V (2018). What Has Come out from Phytomedicines and Herbal Edibles for the Treatment of Cancer? ChemMedChem 13:1854-1872.

Brun S, Schall N, Bonam SR, Bigauta K, Mensah-Nyagana AG, de Sèze J, Muller S (2018). An autophagy-targeting peptide to treat chronic inflammatory demyelinating polyneuropathies. Journal of Autoimmunity 92:114-125.

Li, B., Wang, F., Schall, N., Muller, S. (2018) Rescue of autophagy and lysosome defects in salivary glands of MRL/lpr mice by a therapeutic phosphopeptide. Journal of Autoimmunity 90: 132-145.

Murera, D., Arbogast, F., Arnold, J., Bouis, D., Muller, S., Gros, F. (2018) CD4 T cell autophagy is integral to memory maintenance. Scientific Report 8:5951.

Muller, S. (2018) Excipients: not so inert? When the excipient plays the role of an active substance, as exemplified in systemic lupus. Swiss Medical Weekly 148:w14631.

Wilhelm M, Wang F, Schall N, Kleinmann JF, Faludi M, Nashi EP, Sibilia J, Martin T, Schaeffer E, Muller S (2018). Lupus Regulator Peptide P140 Represses B Cell Differentiation by Reducing HLA Class II Molecule Overexpression. Arthritis Rheumatol 70:1077-1088.

Kökten T, Gibot S, Lepage P, D’Alessio S, Hablot J, Ndiaye NC, Busby-Venner H, Monot C, Garnier B, Moulin D, Jouzeau JY, Hansmannel H, Danese S, Guéant JL, Muller S, Peyrin-Biroulet L (2018). TREM-1 inhibition restores impaired autophagy activity and reduces colitis in mice. J Crohns Colitis 12:230-244.


Principales publications de 2013 à 2017:

Wang F, Li B, Schall N, Wilhelm M, Muller S (2017). Assessing autophagy in mouse models and patients with systemic autoimmune diseases. Cells 6:16.

Muller S (2017). Autophagie, autoimmunité et maladies autoimmunes. Med Sci 33:319-327.

Brun S, Schall N, Jeltsch-David H, de Sèze J, Muller S (2017). Assessing autophagy in sciatic nerves of a rat model that develops inflammatory autoimmune peripheral neuropathies. Cells 6:30.

Bonam SR, Partidos CD, Halmuthur SKM, Muller S (2017). An overview of novel adjuvants designed for improving vaccine efficacy. Trends Pharmacol Sci 9:771-793.

Muller S, Brun S, René F, de Sèze J, Loeffler JP, Jeltsch-David H (2017). Autophagy in neuroinflammatory diseases. Autoimmunity Rev 16:856-874.

Maueröder C, Schall N, Meyer F, Mahajan A, Garnier B, Hahn J, Kienhöfer D, Hoffmann MH, Muller S (2017). Capability of neutrophils to form NETs is not directly influenced by a CMA-targeting peptide. Front Immunol 8:16.

Jeltsch-David H, Muller S (2016). Autoimmunity, neuroinflammation, pathogen load: a decisive crosstalk in neuropsychiatric SLE. J Autoimmunity 74:13-26.

Muller S, Radic M (2016) Oxidation and mitochondrial origin of NET DNA in lupus. Nature Med 22:126-127.

Arnold J, Murera D, Arbogast F, Fauny JD, Muller S, Gros F (2016). Autophagy is dispensable for B cell development but essential for humoral autoimmune responses. Cell Death Diff 23:853-864.

Wang F, Muller S (2015). Manipulating autophagic processes in autoimmune diseases: a special focus on modulating chaperone-mediated autophagy, an emerging therapeutic target. Front Immunol 6:252.

Macri C, Wang F, Tasset I, Schall N, Page N, Briand JP, Cuervo AM, Muller S (2015). Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide. Autophagy 11:472-486.

Jacquemin J, Schmitt N, Contin-Bordes C, Liu Y, Narayanan P, Seneschal J, Maurouard T, Dougall D, Spence Davizon E, Dumortier H, Douchet I, Raffray L, Richez C, Lazaro E, Duffau P, Truchetet ME, Khoryati L, Mercie P, Couzi L, Merville P, Schaeverbeke T, Viallard JF, Pellegrin JL, Moreau JF, Muller S, Coffman RL, Pascual V, Ueno H, Blanco P (2015). OX40L promotes T follicular helper cell responses in human systemic lupus erythematosus. Immunity 42:1159-1170.

Jeltsch-David H, Muller S (2014). Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. Autoimmunity Rev 13:963-973.

Jeltsch-David H, Muller S (2014). Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers. Nature Rev Neurol 10:579–596.

Gros F, Muller S (2014). Pharmacological regulators of autophagy and their link with modulators of lupus disease. Brit J Pharmacol 171:4337-4359.

Lamanna G, Grillaud M, Macri C, Chaloin O, Muller S, Bianco A (2014). Adamantane-based dendrons for trimerization of the therapeutic P140 peptide. Biomaterials 35:7553-756.

Stricher F, Macri C, Ruff M, Muller S (2013). HSPA8/HSC70 chaperone protein: structure, function and chemical targeting. Autophagy 9:1937–1954.

Zimmer R, Scherbarth HR, Rillo OL, Gomez-Reino J, Muller S (2013). Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial. Ann Rheum Dis 72:1830-1835.